What is the CLP Regulation?

The CLP regulation (Regulation (EC) No. 1272/2008 on classification, labelling and packaging of substances and mixtures) is the new system for labelling substances and mixtures implemented in the EU.

CLP Regulation’s history

The CLP Regulation came into force on 20 January 2009 and replaced the Directives on classifying and labelling hazardous substances (67/548/EEC) and dangerous preparations (1999/45/EC). They were repealed on 1 June 2015. Moreover, the CLP Regulation is linked to the REACH Regulation, which is the European regulation on registering, evaluating, authorising and restricting chemical substances and mixtures.

To this end, the CLP regulation is a key element to guaranteeing safe chemical substance and mixture use in the European Union.

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Commission Delegated Regulation (EU) No. 2023/707

On 31 March 2023 the Commission Delegated Regulation (EU) No. 2023/707, of 19 December 2022, was published, amending the CLP Regulation on hazard classes and criteria for the classification, labelling and packaging of substances and mixtures.

Four new hazard classes were included:

  • Endocrine disruption for human health (categories 1 and 2).

  • Endocrine disruption for the environment (categories 1 and 2).

  • Persistent, bioaccumulative and toxic (PBT) or very persistent, very bioaccumulative (vPvB).

  • Persistent, mobile and toxic, or very persistent, very mobile.

The role of the Spanish Institute of Toxicology and Forensic Science (INTCF) in CLP regulation

Article 45.1 of the CLP states:

Member States shall appoint a body or bodies responsible for receiving information relevant, in particular, for formulating preventative and curative measures, in particular in the event of emergency health response, from importers and downstream users placing mixtures on the market. This information shall include the chemical composition of mixtures placed on the market and classified as hazardous on the basis of their health or physical effects, including the chemical identity of substances in mixtures for which a request for use of an alternative chemical name has been accepted by the Agency, in accordance with Article 24.